Article
Structure-function analysis of the beta regulatory subunit of protein kinase CK2 by targeting embryonic stem cell.
Molecular and cellular biochemistry - 1 Oct 2011
Ziercher Léa, Filhol Odile, Laudet Béatrice, Prudent Renaud, Cochet Claude, Buchou Thierry
Abstract excerpt
Programs that govern stem cell maintenance and pluripotency are dependent on extracellular factors and of intrinsic cell modulators. Embryonic stem (ES) cells with a specific depletion of the gene encoding the regulatory subunit of protein kinase CK2 (CK2β) revealed a viability defect. However, analysis of CK2β functions along the neural lineage established CK2β as a positive regulator for neural stem/progenitor...
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