Article
Association between genetic polymorphisms of CYP2D6 and outcomes in breast cancer patients with tamoxifen treatment.
Journal of Korean medical science - 1 Aug 2011
Park Hyung Seok, Choi Ji-Yeob, Lee Mi-Jeong, Park Seho, Yeo Chang-Woo, Lee Sang Seop, Shin Jae-Gook, Park Byeong-Woo
Abstract excerpt
The aim of the study was to evaluate the association between genetic polymorphisms of CYP2D6 and outcomes in breast cancer patients with tamoxifen treatment. We evaluated the CYP2D6 genetic polymorphisms in 766 breast cancer patients. Among them, 110 patients whose samples were prospectively collected before surgery and treated with tamoxifen were included to evaluate the association between CYP2D6 and outcomes....
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