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Article

MicroRNA-based silencing of Delta/Notch signaling promotes multiple cilia formation

1 Sept 2011

Abstract excerpt

Multiciliated cells lining the surface of some vertebrate epithelia are essential for various physiological processes, such as airway cleansing. Their apical surface is constituted by hundreds of motile cilia, which beat in a coordinated manner to generate directional fluid flow. We recently reported the identification of microRNAs of the miR-449 family as evolutionary conserved key regulators of vertebrate...

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PMID: 21857154
DOI: 10.4161/cc.10.17.17011

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