Article
PGD and aneuploidy screening for 24 chromosomes: advantages and disadvantages of competing platforms.
Reproductive biomedicine online - 1 Dec 2011
Bisignano A, Wells D, Harton G, Munné S
Abstract excerpt
Diagnosis of embryos for chromosome abnormalities, i.e. aneuploidy screening, has been invigorated by the introduction of microarray-based testing methods allowing analysis of 24 chromosomes in one test. Recent data have been suggestive of increased implantation and pregnancy rates following microarray testing. Preimplantation genetic diagnosis for infertility aims to test for gross chromosome changes with the...
Topics
- Aneuploidy
- Computational Biology
- Female
- Fertilization in Vitro
- Humans
- Male
- Polymorphism, Single Nucleotide
- Pregnancy
- Pregnancy Rate
- Preimplantation Diagnosis
- Quality Control
