Article
VKORC1 C1173T and VKORC1 G-1639A gene polymorphisms in Turkish Behçet's patients with ocular and non-ocular involvement.
Ophthalmic genetics - 1 Mar 2014
Demir Helin Deniz, Ortak Hüseyin, Şahin Şemsettin, Ateş Ömer, Benli Ismail, İnanır Ahmet
Abstract excerpt
BACKGROUND: Behçet's disease (BD) is a multisystemic vasculitis with unknown etiology. Vitamin K epoxide reductase complex subunit 1 (VKORC1) is the key enzyme in the formation of active vitamin K that is a cofactor of various coagulation factors. Polymorphisms of the VKORC1 may affect the levels of active forms of vitamin K-dependent coagulation proteins and the tendency to thrombosis. The current study aimed to...
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