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Article

Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data

1 Jan 2011

Abstract excerpt

BACKGROUND: Bacteria employ a variety of adaptation strategies during the course of chronic infections. Understanding bacterial adaptation can facilitate the identification of novel drug targets for better treatment of infectious diseases. Transcriptome profiling is a comprehensive and high-throughput approach for characterization of bacterial clinical isolates from infections. However, exploitation of the...

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PMID: 21851621
DOI: 10.1186/1471-2180-11-184

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