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Article

Functional significance of the ATP‐binding cassette transporter B6 in hepatocellular carcinoma

28 Jul 2011

Abstract excerpt

ABCB6 is a mitochondrial transporter that regulates porphyrin biosynthesis. ABCB6 expression is upregulated in hepatocellular carcinoma (HCC) but the significance of this upregulation to HCC is not known. In the present study, we investigated: 1) ABCB6 expression in 18 resected human hepatocellular carcinoma (HCC) tissues and 3 human hepatoma cell lines; 2) pattern of ABCB6 expression during liver disease...

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PMID: 21849266
DOI: 10.1016/j.molonc.2011.07.005

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