Article
Epithelial Bmp (Bone morphogenetic protein) signaling for bulbourethral gland development: a mouse model for congenital cystic dilation.
Congenital anomalies - 1 Sept 2011
Omori Akiko, Harada Masayo, Ohta Sho, Villacorte Mylah, Sugimura Yoshiki, Shiraishi Taizou, Suzuki Kentaro, Nakagata Naomi, Ito Takaaki, Yamada Gen
Abstract excerpt
The bulbourethral gland (BUG) is a male-specific organ, which secretes part of the semen fluid. As the BUG is located in the deep pelvic floor, its developmental process is still unclear. Bone morphogenetic protein (Bmp) signaling plays pivotal roles in various organs. However, the function of Bmp signaling for BUG development is still unclear. The present study aimed to elucidate the role of Bmp signaling in the...
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