Article
Genetic associations with metabolic syndrome and its quantitative traits by race/ethnicity in the United States.
Metabolic syndrome and related disorders - 1 Dec 2011
Vassy Jason L, Shrader Peter, Yang Quanhe, Liu Tiebin, Yesupriya Ajay, Chang Man-Huei, Dowling Nicole F, Ned Renée M, Dupuis Josée, Florez Jose C, Khoury Muin J, Meigs James B
Abstract excerpt
BACKGROUND: Elevated insulin resistance (IR), triglycerides (TG), body mass index (BMI), and waist circumference (WC) are features of the metabolic syndrome. Although several single-nucleotide polymorphisms (SNPs) associated with these traits have been reported, no study has reported their risk allele frequencies and effect sizes among the major U.S. race/ethnic groups in a nationally representative sample....
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