Article
Frequent loss of the BLID gene in early-onset breast cancer.
Cytogenetic and genome research - 1 Jan 2011
Cavalli L R, Noone A-M, Makambi K H, Rone J D, Kasid U N, Haddad B R
Abstract excerpt
The BH3-like motif-containing inducer of cell death (BLID) is an intronless gene localized on 11q24.1. Loss of that region has frequently been reported in early-onset breast cancer and is significantly associated with poor prognosis and reduced survival. Downregulation of BLID is associated with younger age, triple-negative phenotype, and reduced disease-free and overall survival of breast cancer patients. In...
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