Article
Single nucleotide polymorphism (SNP)-based differentiation of Shigella isolates by pyrosequencing.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2011
Hayford Alice E, Mammel Mark K, Lacher David W, Brown Eric W
Abstract excerpt
Analysis of single nucleotide polymorphisms (SNPs) is an important genetic tool that provides molecular markers for rapid differentiation of closely related strains. We have applied SNP discovery and analysis for distinguishing each of the four Shigella serogroups (Boydii, Dysenteriae, Flexneri, and Sonnei) and for discriminating individual strains within the same serogroup by using 24 SNPs selected from nine...
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