Article
Lack of association between polymorphisms in the interleukin-1 gene cluster and familial thrombophilia.
Thrombosis research - 1 May 2012
Marsden Luke, Cox Angela, Makris Mike, Daly Martina E
Abstract excerpt
INTRODUCTION: Inflammation and venous thrombosis are intimately linked, and there is evidence that levels of inflammatory cytokines influence risk of venous thrombosis. We investigated the hypothesis that allelic variation within the IL-1 gene cluster, which encompasses the genes encoding the inflammatory cytokines IL-1α and IL-1β and the competitive IL-1 receptor antagonist, is associated with venous thrombosis...
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