Hypertrophic cardiomyopathy: from genetics to treatment.

Abstract excerpt

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is the prototypic form of pathological cardiac hypertrophy. HCM is an important cause of sudden cardiac death in the young and a major cause of morbidity in the elderly. DESIGN: We discuss the clinical implications of recent advances in the molecular genetics of HCM. RESULTS: The current diagnosis of HCM is neither adequately sensitive nor specific. Partial...

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