Article
[Targeted therapy in lung cancer: molecular testing using cytological specimens].
Revue medicale suisse - 27 Jul 2011
Pusztaszeri M, Pache J-C, Mach N, Soccal P M, McKee T
Abstract excerpt
Important advances in lung cancer treatment have been made over the last decade. Several drugs designed to target molecular pathways involved in cancer-cell growth and survival have been shown to be effective in a selected fraction (<20%) of non-small cell lung cancer patients. Somatic mutations in several genes (i.e.: EGFR and KRAS) can predict patient's response to targeted therapies. Those mutations are...
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