Article
Refractory asthma: importance of bronchoscopy to identify phenotypes and direct therapy.
Chest - 1 Mar 2012
Good James T, Kolakowski Christena A, Groshong Steve D, Murphy James R, Martin Richard J
Abstract excerpt
BACKGROUND: The pathophysiology of refractory asthma is not well understood; thus, treatment modalities are not targeted to specific phenotypes but rather to a broad-based treatment approach. The objective of this study was to develop refractory asthma phenotypes based on bronchoscopic evaluation and to develop from this information specific, directed, personalized therapy. METHODS: Fifty-eight patients with...
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