Article
Transcriptional responses of host peripheral blood cells to tuberculosis infection.
Tuberculosis (Edinburgh, Scotland) - 1 Sept 2011
Lesho Emil, Forestiero Francisco J, Hirata Mario H, Hirata Rosario D, Cecon Leticia, Melo Fernando F, Paik Sun H, Murata Yoko, Ferguson Earl W, Wang Zhining, Ooi Guck T
Abstract excerpt
Host responses following exposure to Mycobacterium tuberculosis (TB) are complex and can significantly affect clinical outcome. These responses, which are largely mediated by complex immune mechanisms involving peripheral blood cells (PBCs) such as T-lymphocytes, NK cells and monocyte-derived macrophages, have not been fully characterized. We hypothesize that different clinical outcome following TB exposure will...
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