Article
Black patients of African descent and HLA-DRB1*15:03 frequency overrepresented in epidermolysis bullosa acquisita.
The Journal of investigative dermatology - 1 Dec 2011
Zumelzu Coralie, Le Roux-Villet Christelle, Loiseau Pascale, Busson Marc, Heller Michel, Aucouturier Françoise, Pendaries Valérie, Lièvre Nicole, Pascal Francis, Brette Marie-Dominique, Doan Serge, Charron Dominique, Caux Fréderic, Laroche Liliane, Petit Antoine, Prost-Squarcioni Catherine
Abstract excerpt
Epidermolysis bullosa acquisita (EBA) is a rare autoimmune bullous disease (AIBD). However, higher EBA incidence and predisposing genetic factor(s) involving an HLA haplotype have been suspected in some populations. This retrospective study assessed the overrepresentation of black patients with EBA, its link with HLA-DRB1*15:03, and their clinical and immunological characteristics. Between 2005 and 2009, 7/13...
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