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Isolation and characterization of eight tumor necrosis factor-induced gene sequences from human fibroblasts.

1 May 1990

Abstract excerpt

A lambda cDNA library was prepared from polyadenylated RNA isolated from quiescent human diploid FS-4 fibroblasts stimulated with tumor necrosis factor for 3 h. Differential screening was used to isolate cDNA sequences that are stimulated by tumor necrosis factor. Eight distinct tumor necrosis factor-stimulated gene sequences (designated TSG-1, -6, -8, -12, -14, -21, -27, and -37) were partially sequenced and...

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PMID: 2183014
DOI: 10.1128/mcb.10.5.1982

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