Article
Transforming growth factor β signaling pathway associated gene polymorphisms may explain lower breast cancer risk in western Indian women.
PloS one - 1 Jan 2011
Joshi Narendra N, Kale Mithila D, Hake Sujata S, Kannan Sadhana
Abstract excerpt
Transforming growth factor β1 (TGFB1) T29C and TGF β receptor type 1 (TGFBR1) 6A/9A polymorphisms have been implicated in the modulation of risk for breast cancer in Caucasian women. We analyzed these polymorphisms and combinations of their genotypes, in pre menopausal breast cancer patients (N = 182) and healthy women (N = 236) from western India as well as in breast cancer patients and healthy women from the...
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