Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms associated with steroids metabolism and insulin action in polycystic ovary syndrome.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Mar 2012

Ramos Cirilo Priscila Daniele, Rosa Fabíola Encinas, Moreira Ferraz Maria Fernanda, Rainho Cláudia Aparecida, Pontes Anaglória, Rogatto Silvia Regina

Abstract excerpt

Polycystic ovary syndrome (PCOS) is an endocrinopathy associated with infertility, diabetes and cardiovascular events. This study aimed to correlate polymorphisms of genes involved in the biosynthesis and metabolism of steroids and insulin action (CYP17A1, CYP19A1, AR, ESR1, ESR2, INSR, IGF2 and PAI1) with clinical and biochemical parameters of PCOS. DNA was extracted from peripheral blood samples obtained from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aromatase
Share to Estrogen Receptor alpha

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Estrogen Receptor beta

Share to Plasminogen Activator Inhibitor 1

Share to Polycystic Ovary Syndrome

Share to Receptor, Insulin

Share to Steroid 17-alpha-Hydroxylase

Share to Steroids

Source

Identifiers

PMID: 21824047
DOI: 10.3109/09513590.2011.593661

Genes

IGF2
INSR
ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms associated with steroids metabolism and insulin action in polycystic ovary syndrome.PMID 21824047Read ↗

Genomic association of SNPs rs4077582 of CYP11A1 and rs700519 of CYP19A1 genes with polycystic ovarian syndrome.Semantic proximity Read ↗

Genetic association study from North India to analyze association of CYP19A1 and CYP17A1 with polycystic ovary syndrome.Semantic proximity Read ↗

The role of polymorphism in various potential genes on polycystic ovary syndrome susceptibility and pathogenesis.Semantic proximity Read ↗

Identifying genes associated with the development of human polycystic ovary syndromeSemantic proximity Read ↗

Genetic Markers of Polycystic Ovary Syndrome: Emphasis on Insulin ResistanceSemantic proximity Read ↗

Biochemical Characterization and Molecular Determination of Estrogen Receptor-α (ESR1 PvuII-rs2234693 T>C) and MiRNA-146a (rs2910164 C>G) Polymorphic Gene Variations and Their Association with the Risk of Polycystic Ovary SyndromeSemantic proximity Read ↗

Estrogen receptor αlpha gene (ESR1) PvuII and XbaI polymorphisms are associated to metabolic and proinflammatory factors in polycystic ovary syndrome.Semantic proximity Read ↗

Association of GWAS identified INSR variants (rs2059807 & rs1799817) with polycystic ovarian syndrome in Indian women.Semantic proximity Read ↗

Metabolic and hormonal profiling in polycystic ovarian syndrome: insights into INSR gene variations.Semantic proximity Read ↗

Potential genetic polymorphisms predicting polycystic ovary syndromeSemantic proximity Read ↗

A Comprehensive Overview of Common Polymorphic Variants in Genes Related to Polycystic Ovary Syndrome.Semantic proximity Read ↗

Present status of understanding on the genetic etiology of polycystic ovary syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.