Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanism of EGER-related cancer drug resistance.

Anti-cancer drugs - 1 Nov 2011

Wei Xiaona

Abstract excerpt

Drug resistance in cancer arises from a complex range of biochemical and molecular events, which ultimately result in tumor cell survival. Identifying key genes and signal pathways involved in the molecular mechanisms of drug resistance is essential for establishment of new drug targets for preventing further resistance development and spreading. Epidermal growth factor receptor (EGFR) was the first growth factor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Class I Phosphatidylinositol 3-Kinases
Share to Oncogene Protein v-akt

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phosphatidylinositol 3-Kinases

Share to Proto-Oncogene Proteins B-raf

Share to Proto-Oncogene Proteins p21(ras)

Share to PTEN Phosphohydrolase

Share to ras Proteins

Source

Identifiers

PMID: 21822122
DOI: 10.1097/CAD.0b013e32834a149c

Genes

EGFR
BRAF
KRAS
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanism of EGER-related cancer drug resistance.PMID 21822122Read ↗

Genetic alterations shaping tumor response to anti-EGFR therapies.Semantic proximity Read ↗

Anticancer drug resistance: An update and perspective.Semantic proximity Read ↗

Updates on altered signaling pathways in tumor drug resistanceSemantic proximity Read ↗

Drug resistance mechanisms in cancers: Execution of pro-survival strategiesSemantic proximity Read ↗

Mutations and response to epidermal growth factor receptor inhibitors.Semantic proximity Read ↗

Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor.Semantic proximity Read ↗

The Different Mechanisms of Cancer Drug Resistance: A Brief ReviewSemantic proximity Read ↗

Cracking the EGFR code: Cancer biology, resistance mechanisms, and future therapeutic frontiers.Semantic proximity Read ↗

Mechanisms of resistance to EGFR-targeted therapies in colorectal cancer: more than just geneticsSemantic proximity Read ↗

Circumventing Cancer Drug Resistance in the Era of Personalized MedicineSemantic proximity Read ↗

Mechanisms and insights into drug resistance in cancerSemantic proximity Read ↗

The quest to overcome resistance to EGFR-targeted therapies in cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.