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Article

Tyrosine-96 as a natural spectroscopic probe of the cytochrome P-450cam active site.

Biochemistry - 6 Feb 1990

Atkins W M, Sligar S G

Abstract excerpt

The previously described correlation between the ferric spin equilibrium of cytochrome P-450cam and the environmental polarity of tyrosine residues (Fisher et al., 1986) has been further examined with the use of site-directed mutagenesis and active-site affinity reagents. Whereas the wild-type demonstrates an increase in environmental polarity of approximately one tyrosine residue, the mutant protein Y96F, in...

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Identifiers

PMID: 2182119
DOI: 10.1021/bi00457a024

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Tyrosine-96 as a natural spectroscopic probe of the cytochrome P-450cam active site.PMID 2182119Read ↗

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