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Article

A comprehensively molecular haplotype-resolved genome of a European individual.

Genome research - 1 Oct 2011

Suk Eun-Kyung, McEwen Gayle K, Duitama Jorge, Nowick Katja, Schulz Sabrina, Palczewski Stefanie, Schreiber Stefan, Holloway Dustin T, McLaughlin Stephen, Peckham Heather, Lee Clarence, Huebsch Thomas, Hoehe Margret R

Abstract excerpt

Independent determination of both haplotype sequences of an individual genome is essential to relate genetic variation to genome function, phenotype, and disease. To address the importance of phase, we have generated the most complete haplotype-resolved genome to date, "Max Planck One" (MP1), by fosmid pool-based next generation sequencing. Virtually all SNPs (>99%) and 80,000 indels were phased into haploid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21813624
DOI: 10.1101/gr.125047.111
PMCID: PMC3202284

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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