Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas

Abstract excerpt

BACKGROUND: High serum levels of estradiol are associated with increased risk of postmenopausal breast cancer. Little is known about the gene expression in normal breast tissue in relation to levels of circulating serum estradiol. METHODS: We compared whole genome expression data of breast tissue samples with serum hormone levels using data from 79 healthy women and 64 breast cancer patients. Significance...

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