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Article

Proliferation-associated POU4F2/Brn-3b transcription factor expression is regulated by oestrogen through ERα and growth factors via MAPK pathway.

Breast cancer research : BCR - 17 Jan 2011

Ounzain Samir, Bowen Samantha, Patel Chandrakant, Fujita Rieko, Heads Richard J, Budhram-Mahadeo Vishwanie S

Abstract excerpt

INTRODUCTION: In cancer cells, elevated transcription factor-related Brn-3a regulator isolated from brain cDNA (Brn-3b) transcription factor enhances proliferation in vitro and increases tumour growth in vivo whilst conferring drug resistance and migratory potential, whereas reducing Brn-3b slows...

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Identifiers

PMID: 21241485
DOI: 10.1186/bcr2809
PMCID: PMC3109571

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21241485-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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