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Article

Genetic variations in the dopaminergic system and alcohol use: a system-level analysis.

Addiction biology - 1 Mar 2012

Chen Chunhui, Chen Chuansheng, Moyzis Robert, He Qinghua, Li He, Li Jin, Zhu Bi, Lessard Jared, Stern Hal, Dong Qi

Abstract excerpt

Alcohol use is highly heritable and has been associated with many gene variants, including those related to dopamine (DA). However, single gene association studies have shown inconsistent and small effects. Using a system-level approach, the current study aimed to estimate the overall effect of genetic variations in the DA system on alcohol use among male drinkers. One hundred seventy-six male college students...

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Identifiers

PMID: 21812867
DOI: 10.1111/j.1369-1600.2011.00348.x

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