Article
The PLA2G6 gene in early-onset Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society - 1 Nov 2011
Kauther Kai Michael, Höft Christine, Rissling Ida, Oertel Wolfgang H, Möller Jens Carsten
Abstract excerpt
BACKGROUND: The definite etiology of neurodegenerative disorders such as Parkinson's disease (PD) is still unknown. Because of its role in the generation of reactive oxygen species and its association with neurodegeneration with brain iron accumulation, a possible involvement of calcium-independent group VI phospholipase A(2) (iPLA(2)-VI) in the pathogenesis of PD has been proposed. METHODS: In this study we...
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