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Article

The role of the PLA2G6 gene in neurodegenerative diseases.

Ageing research reviews - 1 Aug 2023

Deng Xinyue, Yuan Lamei, Jankovic Joseph, Deng Hao

Abstract excerpt

PLA2G6-associated neurodegeneration (PLAN) represents a continuum of clinically and genetically heterogeneous neurodegenerative disorders with overlapping features. Usually, it encompasses three autosomal recessive diseases, including infantile neuroaxonal dystrophy or neurodegeneration with brain iron accumulation (NBIA) 2A, atypical neuronal dystrophy with childhood-onset or NBIA2B, and adult-onset...

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PMID: 37236368
DOI: 10.1016/j.arr.2023.101957

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