Article
Effect of Heterogeneous Distribution of Monosomy 3 on Prognosis in Uveal Melanoma
1 Aug 2011
Abstract excerpt
CONTEXT: Fluorescence in situ hybridization (FISH) analyses on tumor sections and on isolated nuclei showed that even low numbers of cells with monosomy of chromosome 3 adversely affected survival. OBJECTIVE: To determine what percentage of uveal melanoma cells with monosomy of chromosome 3 influences patient mortality. DESIGN: To determine the presence of monosomy 3, karyotyping and FISH on cultured cells and...
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