Article
Regulation of the operon encoding ribonucleotide reductase: role of the negative sites in nrd repression.
Journal of bacteriology - 1 Apr 1990
Tuggle C K, Fuchs J A
Abstract excerpt
Expression of the nrd genes was previously shown to be controlled by both positive and negative regulation (C. K. Tuggle and J. A. Fuchs, EMBO J. 5:1077-1085, 1986). Two regions, one located 5' and one located 3' of the nrd promoter (nrdP), were identified as negative regulatory sites since deletion of these sequences increased nrd expression. These regions of DNA have sequence similarities, and a looping...
Topics
- Base Sequence
- Deoxyribonuclease I
- Enzyme Repression
- Escherichia coli
- Galactokinase
- Gene Expression Regulation, Bacterial
- Genes, Regulator
- Molecular Sequence Data
- Operon
- Phenotype
- Plasmids