Article
High abundance of CD271(+) multipotential stromal cells (MSCs) in intramedullary cavities of long bones.
Bone - 1 Feb 2012
Cox George, Boxall Sally A, Giannoudis Peter V, Buckley Conor T, Roshdy Tarek, Churchman Sarah M, McGonagle Dennis, Jones Elena
Abstract excerpt
Aspiration of iliac crest bone marrow (ICBM) remains the most frequent technique used in harvesting multipotential stromal cells (MSCs) for bone regeneration. Although this tissue type is easily accessed by a surgeon, it has a low frequency of MSCs, which is significant given the high cell numbers required for bone regeneration strategies. Lipoaspirates possess higher MSC frequencies, albeit cells with a...
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