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Article

Mutation analysis of the SLX4/FANCP gene in hereditary breast cancer.

Breast cancer research and treatment - 1 Dec 2011

Landwehr Rosa, Bogdanova Natalia V, Antonenkova Natalia, Meyer Andreas, Bremer Michael, Park-Simon Tjoung-Won, Hillemanns Peter, Karstens Johann H, Schindler Detlev, Dörk Thilo

Abstract excerpt

SLX4 coordinates three structure-specific endonucleases in the DNA damage response. One subtype of Fanconi anaemia, FA-P, has recently been attributed to biallelic SLX4 gene mutations. To investigate whether monoallelic SLX4 gene defects play some role in the inherited component of breast cancer susceptibility, in this study we resequenced the whole SLX4 coding region and flanking untranslated sections in genomic...

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PMID: 21805310
DOI: 10.1007/s10549-011-1681-1

Genes

SLX4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Mutation analysis of the SLX4/FANCP gene in hereditary breast cancer.PMID 21805310Read ↗

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Identification of low-penetrance alleles, genetic modifiers and mutation analysis in familial breast cancer casesSemantic proximity Read ↗

Whole exome sequencing reveals uncommon mutations in the recently identified Fanconi anemia gene SLX4/FANCP.Semantic proximity Read ↗

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