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Article

Implications of single nucleotide polymorphisms in CD44 exon 2 for risk of breast cancer.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Sept 2011

Zhou Juhua, Nagarkatti Prakash S, Zhong Yin, Zhang Jiajia, Nagarkatti Mitzi

Abstract excerpt

CD44 is a cell-surface glycoprotein involved in many cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis and tumor metastasis, suggesting that CD44 may play an important role in breast cancer development. In this study, we examined whether CD44 exon 2 polymorphisms are associated with increased susceptibility to breast cancer. Direct nucleotide sequencing analysis showed...

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Identifiers

PMID: 21804359
DOI: 10.1097/CEJ.0b013e3283463943
PMCID: PMC3968800

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