Article
The Met-allele of the BDNF Val66Met polymorphism enhances task switching in elderly.
Neurobiology of aging - 1 Dec 2011
Gajewski Patrick D, Hengstler Jan G, Golka Klaus, Falkenstein Michael, Beste Christian
Abstract excerpt
In this study we examined the relevance of the functional brain-derived neurotrophic factor (BDNF) Val66Met polymorphism as a modulator of task-switching performance in healthy elderly by using behavioral and event-related potential (ERP) measures. Task switching was examined in a cue-based and a memory-based paradigm. Val/Val carriers were generally slower, showed enhanced reaction time variability and higher...
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