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Article

Automated Microinjection of Recombinant BCL-X into Mouse Zygotes Enhances Embryo Development

20 Jul 2011

Abstract excerpt

Progression of fertilized mammalian oocytes through cleavage, blastocyst formation and implantation depends on successful implementation of the developmental program, which becomes established during oogenesis. The identification of ooplasmic factors, which are responsible for successful embryo development, is thus crucial in designing possible molecular therapies for infertility intervention. However, systematic...

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PMID: 21799744
DOI: 10.1371/journal.pone.0021687

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