Article
Increased mortality in young candidemia patients associated with presence of a Candida albicans general-purpose genotype.
Journal of clinical microbiology - 1 Sept 2011
Schmid J, Tortorano A M, Jones G, Lazzarini C, Zhang N, Bendall M J, Cogliati M, Wattimena S, Klingspor L
Abstract excerpt
The yeast Candida albicans causes life-threatening candidemia. A general-purpose genotype (GPG; corresponds to clade 1) causes more infections than other C. albicans genotypes. To investigate if GPG strains also cause higher mortality, we developed a duplex PCR assay which was 98% accurate in identifying GPG strains in an international collection of strains typed with probe Ca3. We applied the assay to 635...
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