Article
A DNA polymorphism specific to Candida albicans strains exceptionally successful as human pathogens.
Gene - 11 Jul 2001
Giblin L, Edelmann A, Zhang N, von Maltzahn N B, Cleland S B, Sullivan P A, Schmid J
Abstract excerpt
A large proportion of infection-causing isolates of the yeast Candida albicans belong to a general-purpose genotype, identifiable by fingerprinting with the moderately repetitive sequence Ca3. The high prevalence of this group -- up to 70% in some patient categories -- suggests that its members possess genetic determinants, which enhance their success as pathogens compared to other strains. To find such...
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