Article
The MSS51 gene product is required for the translation of the COX1 mRNA in yeast mitochondria.
Molecular & general genetics : MGG - 1 Oct 1990
Decoster E, Simon M, Hatat D, Faye G
Abstract excerpt
The MSS51 gene product has been previously shown to be involved in the splicing of the mitochondrial pre-mRNA of cytochrome oxidase subunit I (COX1). We show here that it is specifically required for the translation of the COX1 mRNA. Furthermore, the paromocyin-resistance mutation (P454R) which affects the 15S mitoribosomal RNA, interferes, directly or indirectly, with the action of the MSS51 gene product....
Topics
- Alleles
- Blotting, Northern
- Drug Resistance, Microbial
- Electron Transport Complex IV
- Fungal Proteins
- Mitochondria
- Paromomycin
- Protein Biosynthesis
- RNA, Fungal
- RNA, Messenger
- Restriction Mapping