Article
Aberrant translation of cytochrome c oxidase subunit 1 mRNA species in the absence of Mss51p in the yeast Saccharomyces cerevisiae.
Molecular biology of the cell - 1 Feb 2007
Zambrano Andrea, Fontanesi Flavia, Solans Asun, de Oliveira Rodrigo Leite, Fox Thomas D, Tzagoloff Alexander, Barrientos Antoni
Abstract excerpt
Expression of yeast mitochondrial genes depends on specific translational activators acting on the 5'-untranslated region of their target mRNAs. Mss51p is a translational factor for cytochrome c oxidase subunit 1 (COX1) mRNA and a key player in down-regulating Cox1p expression when subunits with which it normally interacts are not available. Mss51p probably acts on the 5'-untranslated region of COX1 mRNA to...
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