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Article

Homocysteine and depression in later life.

Archives of general psychiatry - 1 Nov 2008

Almeida Osvaldo P, McCaul Kieran, Hankey Graeme J, Norman Paul, Jamrozik Konrad, Flicker Leon

Abstract excerpt

CONTEXT: The prevalence of depression in later life increases with plasma total homocysteine concentration (tHcy). High tHcy accounts for about 15% of prevalent cases, but observational studies are prone to confounding and bias. Genetic association studies are not prone to the same sources of error and offer an opportunity to explore the consistency and external validity of this association. OBJECTIVE: To...

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Source

Identifiers

PMID: 18981340
DOI: 10.1001/archpsyc.65.11.1286

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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