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Article

Maternal folate supply and sex influence gene‐specific DNA methylation in the fetal gut

19 Jul 2011

Abstract excerpt

SCOPE: Epidemiological evidence supports the developmental origins of health and disease hypothesis that developmental under/over-nutrition increases adulthood disease risk. Epigenetic markings are one potential mechanism mediating these effects. Altered folate supply may influence methyl group availability for DNA methylation. We reported low folate supply in utero was associated with reduced global DNA...

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PMID: 21770049
DOI: 10.1002/mnfr.201100150

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