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Article

SlyA protein activates fimB gene expression and type 1 fimbriation in Escherichia coli K-12.

The Journal of biological chemistry - 16 Sept 2011

McVicker Gareth, Sun Lei, Sohanpal Baljinder K, Gashi Krishna, Williamson Richard A, Plumbridge Jacqueline, Blomfield Ian C

Abstract excerpt

We have demonstrated that SlyA activates fimB expression and hence type 1 fimbriation, a virulence factor in Escherichia coli. SlyA is shown to bind to two operator sites (O(SA1) and O(SA2)), situated between 194 and 167 base pairs upstream of the fimB transcriptional start site. fimB expression is derepressed in an hns mutant and diminished by a slyA mutation in the presence of H-NS only. H-NS binds to multiple...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21768111
DOI: 10.1074/jbc.M111.266619
PMCID: PMC3173223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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