Article
Mechanisms of gap gene expression canalization in the Drosophila blastoderm.
BMC systems biology - 1 Jan 2011
Gursky Vitaly V, Panok Lena, Myasnikova Ekaterina M, Manu, Samsonova Maria G, Reinitz John, Samsonov Alexander M
Abstract excerpt
BACKGROUND: Extensive variation in early gap gene expression in the Drosophila blastoderm is reduced over time because of gap gene cross regulation. This phenomenon is a manifestation of canalization, the ability of an organism to produce a consistent phenotype despite variations in genotype or environment. The canalization of gap gene expression can be understood as arising from the actions of attractors in the...
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