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Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort.

Clinical endocrinology - 1 Mar 2012

Chang Yi-Cheng, Chiu Yen-Feng, Liu Pi-Hua, Shih Kuang-Chung, Lin Ming-Wei, Sheu Wayne H-H, Quertermous Thomas, Curb Jess David, Hsiung Chano A, Lee Wei-Jei, Lee Po-Chu, Chen Yuan-Tsong, Chuang Lee-Ming

Abstract excerpt

BACKGROUND: A recent genome-wide association study for type 2 diabetes in Han Chinese identified several novel genetic variants. We investigated their associations with quantitative measures to explore the mechanism by which these variants influence glucose homoeostasis. We also examined whether these variants predict progression to diabetes in a large prospective family based Chinese cohort. METHODS: Five single...

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PMID: 21767287
DOI: 10.1111/j.1365-2265.2011.04175.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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