Article
Microarray analysis of the infrapatellar fat pad in knee osteoarthritis: relationship with joint inflammation.
The Journal of rheumatology - 1 Sept 2011
Gandhi Rajiv, Takahashi Mark, Virtanen Carl, Syed Khalid, Davey J Roderick, Mahomed Nizar N
Abstract excerpt
OBJECTIVE: To examine differences in genes involved in fat metabolism, energy homeostasis, adipogenesis, and inflammation between endstage and early-stage knee osteoarthritis (OA) infrapatellar fat pads (IFP). METHODS: Twenty-nine endstage and 5 early-stage primary OA IFP were harvested at knee surgery. Total RNA was extracted, labeled, and hybridized to whole-genome expression arrays. Unsupervised analysis of...
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