Article
[Combined application of ciprofloxacin and tobramycin on mutant selective windows of ciprofloxacin against Pseudomonas aeruginosa].
Zhonghua yi xue za zhi - 31 May 2011
Liu Ming-tao, Sheng Mei-yan, Zhang Yun, Li Yu
Abstract excerpt
OBJECTIVE: To observe whether the mutant selective windows (MSW) of ciprofloxacin would be reduced after its combination against Pseudomonas aeruginosa in rabbits. METHODS: Firstly the minimal inhibitory concentration (MIC), mutant prevention concentration (MPC), mutant selective windows (MSW, MPC-MIC) and selective indices (SI, MPC/MIC) of ciprofloxacin and tobramycin were measured in vitro respectively with...
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