Article
Brain perfusion patterns in familial frontotemporal lobar degeneration.
Neurology - 26 Jul 2011
Seelaar H, Papma J M, Garraux G, de Koning I, Reijs A E, Valkema R, Rozemuller A J M, Salmon E, van Swieten J C
Abstract excerpt
OBJECTIVE: Frontotemporal lobar degeneration (FTLD) is a clinically, genetically, and pathologically heterogeneous disorder. The aim of this study was to compare clinical features and perfusion patterns on SPECT of patients with familial FTLD-TAR DNA binding protein 43 kDa (TDP) and MAPT mutations. METHODS: Patients were included if they had MAPT or GRN mutations, positive family history with pathologically...
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