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Article

Follicle-stimulating hormone receptor polymorphism (G-29A) is associated with altered level of receptor expression in Granulosa cells.

The Journal of clinical endocrinology and metabolism - 1 Sept 2011

Desai Swapna S, Achrekar Swati K, Pathak Bhakti R, Desai Sadhana K, Mangoli Vijay S, Mangoli Ranjana V, Mahale Smita D

Abstract excerpt

CONTEXT: Polymorphisms of the FSHR gene are associated with variable ovarian response to FSH stimulation in subjects undergoing in vitro fertilization (IVF) treatment. The type of ovarian response is correlated with the level of FSH receptor (FSHR) expression on granulosa cells. OBJECTIVE: We investigated whether the polymorphism at position -29 in the promoter of the FSHR gene may contribute in altered receptor...

Topics

Adult
Female
Follicle Stimulating Hormone
Genotype
Granulosa Cells
Humans
Infertility, Female
Ovary
Ovulation Induction
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Receptors, FSH

Source

Identifiers

PMID: 21752882
DOI: 10.1210/jc.2011-1064

Genes

FSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Follicle-stimulating hormone receptor polymorphism (G-29A) is associated with altered level of receptor expression in Granulosa cells.PMID 21752882Read ↗

Poor ovarian response to gonadotrophin stimulation is associated with FSH receptor polymorphism.Semantic proximity Read ↗

The carriers of the A/G-G/G allelic combination of the c.2039 A>G and c.-29 G>A FSH receptor polymorphisms retrieve the highest number of oocytes in IVF/ICSI cycles.Semantic proximity Read ↗

Association of allelic combinations of FSHR gene polymorphisms with ovarian response.Semantic proximity Read ↗

The FSHR G-29A variant is not associated with the ovarian response to exogenous FSH stimulation.Semantic proximity Read ↗

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