Article
Association of follicle-stimulating hormone receptor polymorphisms with ovarian response in Chinese women: a prospective clinical study.
PloS one - 1 Jan 2013
Yan Yuanliang, Gong Zhicheng, Zhang Lu, Li Yanping, Li Xiong, Zhu Lin, Sun Lunquan
Abstract excerpt
BACKGROUND: Follicular stimulating hormone (FSH) is a glycoprotein and widely used for the treatment of infertility; FSH action is mediated by FSH receptor (FSHR), SNPs of which determine the ovarian response. Two polymorphisms of the FSHR gene were identified, which caused a change of threonine (T) to alanine (A) at position 307 and asparagine (N) to serine(S) at position 680. Both polymorphic sites give rise to...
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