Article
LUPA: a European initiative taking advantage of the canine genome architecture for unravelling complex disorders in both human and dogs.
Veterinary journal (London, England : 1997) - 1 Aug 2011
Lequarré Anne-Sophie, Andersson Leif, André Catherine, Fredholm Merete, Hitte Christophe, Leeb Tosso, Lohi Hannes, Lindblad-Toh Kerstin, Georges Michel
Abstract excerpt
The domestic dog offers a unique opportunity to explore the genetic basis of disease, morphology and behaviour. Humans share many diseases with our canine companions, making dogs an ideal model organism for comparative disease genetics. Using newly developed resources, genome-wide association studies in dog breeds are proving to be exceptionally powerful. Towards this aim, veterinarians and geneticists from 12...
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